Resurgence of SARS-CoV-2: Detection by community viral surveillance

Science. 2021 May 28;372(6545):990-995. doi: 10.1126/science.abf0874. Epub 2021 Apr 23.

Abstract

Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Basic Reproduction Number
  • COVID-19 / diagnosis
  • COVID-19 / epidemiology*
  • COVID-19 Nucleic Acid Testing
  • Child
  • Child, Preschool
  • England / epidemiology
  • Epidemiological Monitoring*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pandemics
  • Prevalence
  • Public Health Surveillance*
  • SARS-CoV-2
  • Young Adult