Treatment of Epilepsy Associated with Common Chromosomal Developmental Diseases

Open Life Sci. 2020 Feb 28:15:21-29. doi: 10.1515/biol-2020-0003. eCollection 2020.

Abstract

Chromosomal diseases are heterogeneous conditions with complex phenotypes, which include also epileptic seizures. Each chromosomal syndrome has a range of specific characteristics regarding the type of seizures, EEG findings and specific response to antiepileptic drugs, significant in the context of the respective genetic etiology. Therefore, it is very important to know these particularities, in order to avoid an exacerbation of seizures or some side effects. In this paper we will present a review of the epileptic seizures and antiepileptic treatment in some of the most common chromosomal syndromes.

Keywords: antiepileptic drugs; chromosomal diseases; epileptic seizures.