Dissociated response related to corticosteroids in lung cancer treated by immunotherapy: A case report

Clin Case Rep. 2021 Mar 24;9(5):e03973. doi: 10.1002/ccr3.3973. eCollection 2021 May.

Abstract

We report the case of a patient with a complete metastatic adrenal response on Pembrolizumab for metastatic lung cancer. Treatment with a systemic corticosteroid-induced a time-dependent progression at his metastatic site. Surprisingly, after stopping the corticosteroid, we observed a new complete response in long-term adrenal metastases.

Keywords: case reports; immunotherapy; lung neoplasms; programmed cell death 1 receptor; tumor escape.

Publication types

  • Case Reports