Impact of the COVID-19 Pandemic on Keratoplasty and Corneal Eye Banking

Cornea. 2021 Aug 1;40(8):1018-1023. doi: 10.1097/ICO.0000000000002748.

Abstract

Purpose: The purpose of this study was to assess the impact of COVID-19 guidelines for corneal donor tissue screening and the utility of routine postmortem COVID-19 testing of donors intended for surgical use at a single eye bank.

Methods: A retrospective analysis of referrals to and eligible donors from an eye bank between March 1, 2020, and June 30, 2020, was performed, with the same time period in 2019 as a control. Referrals who were not procured because of Eye Bank Association of America COVID-19 guidelines and eye bank-specific restrictions were noted. The results of 1 month of routine postmortem testing performed by the eye bank were examined. Analysis of variance tests were performed to assess the change between donors from 2019 to 2020.

Results: There was a significant reduction in both the number of total referrals to the eye bank (P = 0.044) and donors eligible for surgical transplantation (P = 0.031). Eye Bank Association of America COVID-19 guidelines reduced the number of referrals over this period by 4% to 14%. Of the 266 surgically eligible donors who received postmortem COVID-19 testing in June by the eye bank, 13 resulted positive (4.9%).

Conclusions: Despite a reduction in referrals and eligible corneal transplant donors at a single eye bank, there was a surplus of surgically suitable corneal tissue during the first wave of the COVID-19 pandemic. Eye banks should consider routine postmortem COVID-19 testing to identify asymptomatic infected donors although the risk of transmission of COVID-19 from infected donors is unknown.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • COVID-19 / epidemiology*
  • COVID-19 Nucleic Acid Testing
  • Cornea*
  • Corneal Diseases / surgery
  • Eye Banks / standards
  • Eye Banks / statistics & numerical data*
  • Humans
  • Keratoplasty, Penetrating / statistics & numerical data*
  • Middle Aged
  • Practice Guidelines as Topic
  • Retrospective Studies
  • SARS-CoV-2*
  • Tissue Donors / supply & distribution*
  • Tissue and Organ Procurement / standards*