Echocardiographic Screening for Postoperative Pericardial Effusion in Children

Pediatr Cardiol. 2021 Oct;42(7):1531-1538. doi: 10.1007/s00246-021-02637-7. Epub 2021 Jun 4.

Abstract

Pericardial effusion (PE) after cardiac surgery can be life threatening without timely detection, and the optimal screening method is unknown. We sought to evaluate the role of a surveillance echocardiogram on postoperative day 10 (± 2), determine the incidence of postoperative PE, and identify risk factors. We conducted a retrospective cohort study including all pediatric patients who underwent open heart surgery at a single institution over a 7-month period. To identify risk factors for PE, medical records of patients with PE detected within 6 weeks after surgery (cases) were compared with patients without PE (controls). Of 203 patients, 52 (26%) had PE within 6 weeks; 42 (81%) were trivial-small and 10 (19%) were moderate-large. Twenty-nine (56%) were first detected within 7 days post-operatively, including all cases developing cardiac tamponade (n = 3). An echocardiogram was done 10 (± 2) days post-operatively in 41/52 cases, of which 12/41 (29%) did not have a PE at this time, 24/41 (59%) had a trivial-small PE, and 5/41(12%) had a moderate-large PE; 2 of the latter had no prior detected PE. Closure of an atrial septal defect had the highest incidence of PE (42%). PE cases were associated with postoperative nasopharyngeal detection of a respiratory virus (OR 3.8, p = 0.03). In conclusion, the majority of PE cases were detected within 7 days post-operatively, including all cases subsequently developing cardiac tamponade. Day 10 echocardiography infrequently detected a moderate or large effusion that had previously gone undiagnosed. A positive perioperative nasopharyngeal aspirate for a respiratory virus was associated with postoperative PE.

Keywords: Congenital heart disease; Congenital heart surgery; Pediatrics; Pericardial effusion; Postpericardiotomy syndrome.

MeSH terms

  • Cardiac Tamponade* / diagnostic imaging
  • Cardiac Tamponade* / epidemiology
  • Cardiac Tamponade* / etiology
  • Child
  • Echocardiography
  • Humans
  • Pericardial Effusion* / diagnostic imaging
  • Pericardial Effusion* / epidemiology
  • Pericardial Effusion* / etiology
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / epidemiology
  • Retrospective Studies