Clinical and Laboratory Follow-up After Hospitalization for COVID-19 at an Italian Tertiary Care Center

Michele Spinicci; Iacopo Vellere; Lucia Graziani; Marta Tilli; Beatrice Borchi; Jessica Mencarini; Irene Campolmi; Leonardo Gori; Laura Rasero; Francesco Fattirolli; Iacopo Olivotto; Federico Lavorini; Niccolò Marchionni; Lorenzo Zammarchi; Alessandro Bartoloni; Careggi Post-acute COVID-19 Study Group

doi:10.1093/ofid/ofab049

Clinical and Laboratory Follow-up After Hospitalization for COVID-19 at an Italian Tertiary Care Center

Open Forum Infect Dis. 2021 Feb 4;8(3):ofab049. doi: 10.1093/ofid/ofab049. eCollection 2021 Mar.

Authors

Michele Spinicci^{1

2}, Iacopo Vellere¹, Lucia Graziani¹, Marta Tilli¹, Beatrice Borchi², Jessica Mencarini², Irene Campolmi², Leonardo Gori¹, Laura Rasero³, Francesco Fattirolli^{1

4}, Iacopo Olivotto^{1

5}, Federico Lavorini^{1

6}, Niccolò Marchionni^{1

6}, Lorenzo Zammarchi^{1

2}, Alessandro Bartoloni^{1

2}; Careggi Post-acute COVID-19 Study Group

Collaborators

Careggi Post-acute COVID-19 Study Group:
Carlo Fumagalli, Maria Vittoria Silverii, Luca Ciani, Chiara Zocchi, Luigi Tassetti, Rossella Marcucci, Betti Giusti, Luca Livi, Lorenzo Giovannoni, Paola Parronchi, Fabio Almerigogna, Francesco Annunziato, Alessio Mazzoni, Laura Maggi, Francesco Liotta, Lorenzo Cosmi, Alessandra Vultaggio, Andrea Matucci, Silvia Sticci, Martina Donati, Cecilia Defraia, Fabrizio Giansanti, Daniela Bacherini

Affiliations

¹ Department of Experimental & Clinical Medicine, University of Florence, Florence, Italy.
² Infectious and Tropical Diseases Unit, Careggi University and Hospital, Florence, Italy.
³ Department of Health Science, University of Florence, Florence, Italy.
⁴ Cardiac Rehabilitation Unit, Careggi University Hospital, Florence, Italy.
⁵ Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy.
⁶ Department of Cardiothoracovascular Medicine, Careggi Hospital, Florence, Italy.

Abstract

We evaluated 100 postacute coronavirus disease 2019 (COVID-19) patients a median (interquartile range) of 60 (48-67) days after discharge from the Careggi University Hospital, Italy. Eighty-four (84%) had at least 1 persistent symptom, irrespective of COVID-19 severity. A considerable number of hospital readmissions (10%) and/or infectious diseases (14%) during the postdischarge period were reported.

Keywords: COVID-19; SARS-CoV-2; follow-up; long-term; sequelae.