Icodec Advances the Prospect of Once-Weekly Insulin Injection

J Med Chem. 2021 Jul 8;64(13):8939-8941. doi: 10.1021/acs.jmedchem.1c00983. Epub 2021 Jun 16.

Abstract

Basal glucose control is commonly maintained by a single, once-daily administration of insulin through subcutaneous injection or a continuous pump-infusion. Insulin icodec, a novel ultralong-acting lipidated analog validates the concept of a once-weekly basal injection that is less burdensome, yet equally safe and efficacious as conventional once-daily treatment.

Publication types

  • Introductory Journal Article

MeSH terms

  • Blood Glucose
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / metabolism
  • Drug Administration Schedule
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / chemistry
  • Hypoglycemic Agents / therapeutic use*
  • Infusions, Subcutaneous
  • Insulin / administration & dosage
  • Insulin / analogs & derivatives
  • Insulin / therapeutic use*

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin