Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A Case Report

Juan Carlos Ruiz-Rodríguez; Luis Chiscano-Camón; Clara Palmada; Adolf Ruiz-Sanmartin; Marina García-de-Acilu; Erika Plata-Menchaca; Janire Perurena-Prieto; Manuel Hernandez-Gonzalez; Marcos Pérez-Carrasco; Pere Soler-Palacin; Ricard Ferrer

doi:10.3389/fimmu.2021.665824

Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A Case Report

Front Immunol. 2021 Jun 1:12:665824. doi: 10.3389/fimmu.2021.665824. eCollection 2021.

Authors

Juan Carlos Ruiz-Rodríguez^{1

2}, Luis Chiscano-Camón^{1

2}, Clara Palmada^{1

2}, Adolf Ruiz-Sanmartin^{1

2}, Marina García-de-Acilu^{1

2}, Erika Plata-Menchaca^{1

2}, Janire Perurena-Prieto^{3

4}, Manuel Hernandez-Gonzalez^{3

4}, Marcos Pérez-Carrasco^{1

2}, Pere Soler-Palacin⁵, Ricard Ferrer^{1

2}

Affiliations

¹ Intensive Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.
² Shock, Organ Dysfunction and Resuscitation Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
³ Immunology Division, Vall d'Hebron University Hospital, Barcelona, Spain.
⁴ Diagnostic Immunology Research Group, Vall d'Hebron Research Institute, Barcelona, Spain.
⁵ Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, Spain.

Abstract

Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is characterized by hypercytokinemia leading to overwhelming inflammation. We describe the use of a hemadsorption device as part of the supportive treatment for cytokine storm.

Keywords: SARS-CoV-2; cytokine - immunological terms; hemoadsorption; inflammatory multisystemic syndrome; myocardial injury.

Publication types

Case Reports

MeSH terms

Adolescent
COVID-19 / complications*
COVID-19 / therapy
Hemoperfusion / methods*
Humans
Male
SARS-CoV-2
Systemic Inflammatory Response Syndrome / therapy*

Supplementary concepts

pediatric multisystem inflammatory disease, COVID-19 related