Transient disappearance of CD19+/CD5+ B-lymphocyte clone in peripheral blood in a patient with CLL during SARS-CoV-2-related mild disease

Remo Barnabei; Giulio Di Michele; Antonio Cellini; Gianfranco Amicosante; Mariagrazia Perilli; Pierangelo Bellio; Alessandra Piccirilli; Giuseppe Celenza

doi:10.1002/ccr3.4238

Transient disappearance of CD19⁺/CD5⁺ B-lymphocyte clone in peripheral blood in a patient with CLL during SARS-CoV-2-related mild disease

Clin Case Rep. 2021 Jun 22;9(6):e04238. doi: 10.1002/ccr3.4238. eCollection 2021 Jun.

Authors

Remo Barnabei¹, Giulio Di Michele¹, Antonio Cellini², Gianfranco Amicosante³, Mariagrazia Perilli³, Pierangelo Bellio³, Alessandra Piccirilli³, Giuseppe Celenza³

Affiliations

¹ Clinical Laboratory Regional Hospital "San Salvatore" L'Aquila Italy.
² Department of Infectious Diseases and AIDS Regional Hospital "San Salvatore" L'Aquila Italy.
³ Department of Biotechnological and Applied Clinical Sciences University of L'Aquila L'Aquila Italy.

Abstract

Although lymphopenia is currently considered a good predictor for the prognosis of COVID-19, it must be critically evaluated in patients with CLL, where other clinical markers should be considered to define the prognosis and treatment.

Keywords: CD19+/CD5+ clone; SARS‐CoV‐2; lymphocytic leukemia.

Publication types

Case Reports