Impaired humoral responses to COVID-19 vaccination in patients with lymphoma receiving B-cell-directed therapies

Blood. 2021 Sep 2;138(9):811-814. doi: 10.1182/blood.2021012443.
No abstract available

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Viral / biosynthesis
  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology*
  • Antigens, Viral / immunology*
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • B-Lymphocytes / drug effects
  • B-Lymphocytes / immunology*
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / immunology*
  • Cancer Care Facilities
  • Cohort Studies
  • Female
  • Health Personnel
  • Hematopoietic Stem Cell Transplantation / adverse effects
  • Humans
  • Immunoglobulin G / biosynthesis
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin M / biosynthesis
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology
  • Immunotherapy, Adoptive / adverse effects
  • Institutionalization
  • Lymphoma, B-Cell / immunology*
  • Lymphoma, B-Cell / therapy
  • Lymphoma, T-Cell / immunology
  • Lymphoma, T-Cell / therapy
  • Male
  • Middle Aged
  • Multiple Myeloma / immunology
  • Multiple Myeloma / therapy
  • Nursing Homes
  • Patients
  • Prospective Studies
  • SARS-CoV-2 / immunology*
  • Spike Glycoprotein, Coronavirus / immunology*
  • Vaccination*

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Antineoplastic Agents
  • COVID-19 Vaccines
  • Immunoglobulin G
  • Immunoglobulin M
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2