Autosomal Dominant Polycystic Kidney Disease in which the Polycystic Liver Volume Was Reduced by Rigorous Blood Pressure Control

Tatsuya Suwabe; Yoshifumi Ubara; Daisuke Ikuma; Hiroki Mizuno; Noriko Hayami; Masayuki Yamanouchi; Naoki Sawa

doi:10.2169/internalmedicine.7441-21

Autosomal Dominant Polycystic Kidney Disease in which the Polycystic Liver Volume Was Reduced by Rigorous Blood Pressure Control

Intern Med. 2022 Jan 1;61(1):49-52. doi: 10.2169/internalmedicine.7441-21. Epub 2021 Jul 3.

Authors

Tatsuya Suwabe^{1

2}, Yoshifumi Ubara^{1

2}, Daisuke Ikuma¹, Hiroki Mizuno¹, Noriko Hayami¹, Masayuki Yamanouchi¹, Naoki Sawa^{1

2}

Affiliations

¹ Department of Nephrology, Toranomon Hospital Kajigaya, Japan.
² Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Japan.

Abstract

Polycystic liver disease (PLD) is the most common extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD). However, current treatments for PLD are only supportive. We experienced a case of enlarged kidneys and liver in a 53-year-old Japanese man with ADPKD who was on hemodialysis. He underwent renal transcatheter arterial embolization (TAE) for enlarged kidneys. His blood pressure (BP) decreased after renal TAE, and his liver volume decreased from 5,259 mL to 4,647 mL (11.6% reduction) within 1 year after renal TAE. This case suggests that rigorous blood pressure control may be beneficial for ameliorating enlarged PLD.

Keywords: ADPKD; PLD; blood pressure; polycystic kidney disease; polycystic liver disease.

Publication types

Case Reports

MeSH terms

Blood Pressure
Cysts* / diagnostic imaging
Humans
Kidney / diagnostic imaging
Liver Diseases* / diagnostic imaging
Liver Diseases* / therapy
Male
Middle Aged
Polycystic Kidney, Autosomal Dominant* / complications
Polycystic Kidney, Autosomal Dominant* / therapy