Seventy one files of patients with yeasts septicemia have been studied. This study indicates the influence of factors like age (greater than 50 years), health condition, surgery mainly digestive, severe associated bacterial infections, iatrogenic factors (polyantibiotherapy, catheters, intubation), in the occurrence of these septicemia). Clinical symptoms appear to be mainly fever (93%) accompanied with shudders (26%) and toxi-infectious shock (45%). Diagnosis is made by the isolation of yeasts from the blood cultivated on Sabouraud-Chloramphenicol diphasic medium. Among the responsible yeasts, the genus Candida is predominant (82.2%) with C. albicans (59%) followed by the genera Torulopsis (13.7%) and Trichosporon (2.7%). Medical treatment must associate Amphotericin B and 5 Fluorocytosine.