Imaging of exercise-induced spinal remodeling in elite rowers

Abstract

Objectives: As in-vivo knowledge of training-induced remodeling of intervertebral discs (IVD) is scarce, this study assessed how lumbar IVDs change as a function of long-term training in elite athletes and age-matched controls using compositional Magnetic Resonance Imaging (MRI).

Design: Prospective case-control study.

Methods: Prospectively, lumbar spines of 17 elite rowers (ERs) of the German national rowing team (mean age: 23.9 ± 3.3 years) were imaged on a clinical 3.0 T MRI scanner. ERs were imaged twice during the annual training cycle, i.e., at training intensive preseason preparations (t₀) and 6 months later during post-competition recovery (t₁). Controls (n = 22, mean age: 26.3 ± 1.9 years) were imaged once at corresponding time points (t₀: n = 11; t₁: n = 11). Segment-wise, the glycosaminoglycan (GAG) content of lumbar IVDs (n = 195) was determined using glycosaminoglycan chemical exchange saturation transfer (gagCEST). Linear mixed models were set up to assess the influence of cohort and other variables on GAG content.

Results: During preseason, IVD GAG values of ERs were significantly higher than those of controls (ERs(t₀): 2.58 ± 0.27% (mean ± standard deviations); controls(t₀): 1.43 ± 0.36%; p ≤ 0.001), while during post-competition recovery, such differences were not present anymore (ERs(t₁): 2.11 ± 0.18%; controls(t₁): 1.89 ± 0.24%; p = 0.362).

Conclusions: Professional elite-level rowing is transiently associated with significantly higher gagCEST values, which indicate increased lumbar IVD-GAG content and strong remodeling effects in response to training. Beyond professional rowing, core-strengthening full-body exercise may help to enhance the resilience of the lumbar spine as a potential therapeutic target in treating back pain.

Keywords: Cartilage remodeling; Intervertebral disc; Magnetic resonance imaging; Spine; Water sports; gagCEST.