SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk

Hypertension. 2021 Sep;78(4):983-995. doi: 10.1161/HYPERTENSIONAHA.121.17579. Epub 2021 Aug 30.

Abstract

[Figure: see text].

Keywords: blood pressure; clinical trial; hypertension; renin-angiotensin system; surrogate end point; vascular stiffness.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood Pressure
  • Cardiovascular Diseases / prevention & control*
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / drug therapy*
  • Hypertension / physiopathology
  • Male
  • Middle Aged
  • Prospective Studies
  • Pulse Wave Analysis
  • Vascular Stiffness / drug effects*
  • Vascular Stiffness / physiology