Combination treatment with antibiotics and surgical lung resection for Mycobacterium abscessus pulmonary infection in a breast cancer patient

Hirokazu Tokuyasu; Yoshinari Makino; Yasuaki Kubouchi; Ken Miwa; Hiroshi Miura; Soichiro Ishikawa; Hiromitsu Sakai; Akira Yamasaki

doi:10.1016/j.rmcr.2021.101506

Combination treatment with antibiotics and surgical lung resection for Mycobacterium abscessus pulmonary infection in a breast cancer patient

Respir Med Case Rep. 2021 Sep 3:34:101506. doi: 10.1016/j.rmcr.2021.101506. eCollection 2021.

Authors

Hirokazu Tokuyasu¹, Yoshinari Makino², Yasuaki Kubouchi³, Ken Miwa³, Hiroshi Miura⁴, Soichiro Ishikawa⁵, Hiromitsu Sakai¹, Akira Yamasaki⁵

Affiliations

¹ Division of Respiratory Medicine, Matsue Red Cross Hospital, Shimane, Japan.
² Division of Breast Surgery, Matsue Red Cross Hospital, Shimane, Japan.
³ Division of Respiratory Surgery, Matsue Red Cross Hospital, Shimane, Japan.
⁴ Division of Pathology, Matsue Red Cross Hospital, Shimane, Japan.
⁵ Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan.

Abstract

A 51-year-old woman was admitted to our hospital because of pneumonia after chemotherapy with doxorubicin and cyclophosphamide for left breast cancer. The patient was diagnosed with Mycobacterium abscessus pulmonary infection by the detection of M. abscessus complex (MABC) in sputum cultures. However, MABC is intrinsically resistant to most of the antibacterial agents, and MABC pulmonary disease outcomes with modern antibiotic treatment are currently the worst among all mycobacterial species. We herein report the successful treatment of M. abscessus pulmonary infection by a combination treatment with antibiotics and surgical lung resection.

Keywords: Antibiotics; Anticancer chemotherapy; Breast cancer; Mycobacterium abscessus; Surgical lung resection.

Publication types

Case Reports