Acute Kidney Injury and Acute Respiratory Distress Syndrome

Bryan D Park; Sarah Faubel

doi:10.1016/j.ccc.2021.05.007

Acute Kidney Injury and Acute Respiratory Distress Syndrome

Crit Care Clin. 2021 Oct;37(4):835-849. doi: 10.1016/j.ccc.2021.05.007. Epub 2021 May 27.

Authors

Bryan D Park¹, Sarah Faubel²

Affiliations

¹ Division of Pulmonary Sciences and Critical Care Medicine, Department of Internal Medicine, University of Colorado, Anschutz Medical Campus, 12700 East 19th Avenue, Box C272, Aurora, CO 80045, USA.
² Division of Renal Diseases and Hypertension, Department of Internal Medicine, University of Colorado, Anschutz Medical Campus, 12700 East 19th Avenue, Box C281, Aurora, CO 80045, USA. Electronic address: sarah.faubel@cuanschutz.edu.

Abstract

Acute kidney injury (AKI) complicates approximately a third of all acute respiratory distress syndrome (ARDS) cases, and the combination of the two drastically worsens prognosis. Recent advances in ARDS supportive care have led to improved outcomes; however, much less is known on how to prevent and support patients with AKI and ARDS together. Understanding the dynamic relationship between the kidneys and lungs is crucial for the practicing intensivist to prevent injury. This article summarizes key concepts for the critical care physician managing a patient with ARDS complicated by AKI. Also provided is a discussion of AKI in the COVID-19 era.

Keywords: Acute kidney injury; Acute respiratory distress syndrome; COVID-19; Intensive care unit.

Publication types

Review

MeSH terms

Acute Kidney Injury* / complications
Acute Kidney Injury* / therapy
COVID-19*
Critical Care
Humans
Respiratory Distress Syndrome* / complications
Respiratory Distress Syndrome* / therapy
SARS-CoV-2