SARS-CoV-2 spike protein alleviates atherosclerosis by suppressing macrophage lipid uptake through regulating R-loop formation on MSR1 mRNA

Clin Transl Med. 2021 Sep;11(9):e391. doi: 10.1002/ctm2.391.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Atherosclerosis / genetics*
  • Atherosclerosis / metabolism*
  • Humans
  • Lipid Metabolism / genetics*
  • Macrophages / metabolism
  • R-Loop Structures / genetics*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Scavenger Receptors, Class A / genetics*
  • Scavenger Receptors, Class A / metabolism
  • Spike Glycoprotein, Coronavirus / genetics*
  • Spike Glycoprotein, Coronavirus / metabolism

Substances

  • MSR1 protein, human
  • RNA, Messenger
  • Scavenger Receptors, Class A
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2