Surgical complications after caesarean section: A population-based cohort study

PLoS One. 2021 Oct 5;16(10):e0258222. doi: 10.1371/journal.pone.0258222. eCollection 2021.

Abstract

Background: The rate of caesarean section without medical indication is rising but the risk for surgical complications has not been fully explored.

Methods: Altogether 79 052 women from the Swedish Medical Birth Register who delivered by caesarean section only from 2005 through 2016 were identified and compared with a control group of women delivering vaginally only from the same register and the same period of time. By cross-linking data with the National Patient Register the risks for bowel obstruction, incisional hernia and abdominal pain were analysed, as well as risk factors for these complications. We also analysed acute complications, uterine rupture, and placenta praevia.

Findings: Caesarean section is associated with an increased risk for bowel obstruction (OR 2.92; CI 2.55-3.34), surgery for bowel obstruction (OR 2.12; CI 1.70-2.65), incisional hernia (OR 2.71; CI 2.46-3.00), surgery for incisional hernia (OR 3.35; CI 2.68-4.18), and abdominal pain (OR 1.41; CI 1.38-1.44). Smoking, obesity, and more than one section delivery added significantly to the risk for these complications.

Interpretation: Caesarean section is considered a safe procedure, but awareness of the risk for serious complications is important when deciding on mode of delivery. In this study, more than one section, obesity and smoking significantly increased the risk for complications after caesarean section. Prevention of smoking and obesity among fertile women worldwide must continue to be a high priority.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cesarean Section / adverse effects*
  • Cohort Studies
  • Female
  • Humans
  • Logistic Models
  • Multivariate Analysis
  • Odds Ratio
  • Placenta Previa / epidemiology
  • Placenta Previa / etiology
  • Postoperative Complications / etiology*
  • Pregnancy
  • Risk Factors
  • Uterine Rupture / epidemiology
  • Uterine Rupture / etiology

Grants and funding

PN recieved a grant from the County Council of Västerbotten (RV-644581), https://www.regionvasterbotten.se/forskning The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.