Pulmonary nodules associated with JAK inhibitor therapy in rheumatoid arthritis: A case report

Afr J Thorac Crit Care Med. 2021 Oct 4;27(3):10.7196/AJTCCM.2021.v27i3.116. doi: 10.7196/AJTCCM.2021.v27i3.116. eCollection 2021.

Abstract

Patients with rheumatoid arthritis (RA) may receive Janus kinase (JAK) inhibitors to achieve optimal control of their disease. We report a case of a patient who received a selective JAK1 inhibitor and subsequently developed multiple pulmonary nodules with cavitation. Biopsies confirmed the presence of cryptococcosis and the patient responded well to anti-fungal therapy.

Keywords: Janus kinase inhibitors; opportunistic infections.

Publication types

  • Case Reports