Use of Green Solvents in Metallaphotoredox Cross-Electrophile Coupling Reactions Utilizing a Lipophilic Modified Dual Ir/Ni Catalyst System

J Org Chem. 2021 Dec 3;86(23):17428-17436. doi: 10.1021/acs.joc.1c02013. Epub 2021 Nov 22.

Abstract

Facilitating photoredox coupling reactions in process-friendly green solvents was achieved by the successful application of a dual Ir/Ni catalyst system with enhanced solubility properties. These photochemical reactions (specifically Br-Br sp2-sp3 cross electrophile coupling) are reported in a head to head comparison to the standard di-t-Bu bipyridine ligand Ir/Ni catalyst system. This presentation highlights the benefits of altering the solubility properties of the ligands used in the Ir/Ni dual catalyst.

MeSH terms

  • Catalysis
  • Ligands
  • Nickel*
  • Oxidation-Reduction
  • Solvents

Substances

  • Ligands
  • Solvents
  • Nickel