Frontal bone hyperostotic mass associated with fibrous dysplasia in a male patient with systemic lupus erythematosus (SLE)

Giorgio Giampaoli; Salvatore Chirumbolo; Paola Di Ceglie; Dario Bertossi; Riccardo Nocini

doi:10.1016/j.ijscr.2021.106564

Frontal bone hyperostotic mass associated with fibrous dysplasia in a male patient with systemic lupus erythematosus (SLE)

Int J Surg Case Rep. 2021 Dec:89:106564. doi: 10.1016/j.ijscr.2021.106564. Epub 2021 Nov 18.

Authors

Giorgio Giampaoli¹, Salvatore Chirumbolo², Paola Di Ceglie¹, Dario Bertossi³, Riccardo Nocini⁴

Affiliations

¹ Department of Surgery, Dentistry, Paediatrics and Gynaecology, Unit of Maxillo-Facial Surgery, University of Verona, Verona, Italy.
² Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy. Electronic address: salvatore.chirumbolo@univr.it.
³ Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
⁴ Department of Surgery, Dentistry, Paediatrics and Gynaecology, Unit of Otorhinolaryngology, University of Verona, Verona, Italy.

Abstract

We present a rare clinical report of a 45-year-old man affected by Systemic Lupus Erythematosus (SLE) with a unilateral mass of the left frontal bone, diagnosed as a possible recurrence of fibrous dysplasia. This patient was evaluated with computed tomography (CT scan) and was treated with resection of the mass and reconstruction with splitting a calvarian bone graft. The pathological evidence was suggestive for a bone cavernous haemangioma. No previously described cases of bone dysplasia associated with this systemic syndrome were reported so far. Patient's disease was under stringent control at the time of hospitalization, and the outcome has been successful, even though a mild increase of inflammatory indexes was reported after surgery. This laboratory evidence was transient and not related to further clinical complications.

Keywords: Head and neck; Hemangioma; Hyperostosis; Piezoelectric surgery.