Single-level TLIF Versus LLIF at L4-5: A Comparison of Patient-reported Outcomes and Recovery Ratios

Abstract

Introduction: Both transforaminal lumbar interbody fusion (TLIF) and lateral lumbar interbody fusion (LLIF) are suitable for achievement of lumbar arthrodesis. Comparative studies have observed complications and outcomes without stratification by lumbar level. This study aims to assess patient-reported outcome measures (PROMs) and recovery in TLIF and LLIF at L4-5.

Methods: Patients undergoing primary, elective, single-level, TLIF or LLIF procedures at L4-5 were grouped. Demographics, perioperative characteristics, and postoperative complication rates were collected. PROMs included Patient-Reported Outcome Measurement Information System Physical Function, visual analog scale (VAS) back and leg, Oswestry Disability Index, and 12-Item Short-Form Physical Component Summary, and Mental Component Summary and were collected at preoperative, 6-week, 12-week, 6-month, 1-year, and 2-year time points. Delta values and recovery ratios (RRs) were calculated for all PROMs at all time points. Demographics, perioperative characteristics, and postoperative complications were compared using chi-squared and Student t-test for categorical and continuous variables, respectively. Differences in mean PROMs, delta values, and RR at each time point were evaluated using unpaired Student's t-test.

Results: Three hundred sixty TLIF and 46 LLIF patients were included. Most (54.3%) were men, mean age 56.3 years, and mean body mass index 30.8 kg/m2. Body mass index and insurance significantly differed (P ≤ 0.045, all). TLIF showed significantly greater mean operative time, length of stay, and postoperative narcotic consumption (P < 0.033, all) and greater postoperative nausea/vomiting (P = 0.004). No preoperative PROMs significantly differed. TLIF cohort had significantly greater VAS back at 6 months and VAS leg at 12 weeks and 6 months (P < 0.034, all). No mean delta PROMs or RRs significantly differed.

Discussion: LLIF demonstrated significantly reduced length of stay, postoperative narcotic consumption, and postoperative nausea/vomiting and significantly improved VAS back at 6 months and VAS leg at 12 weeks and 6 months versus TLIF. Although 2-year PROMs and RRs did not significantly differ, our findings may suggest improved midterm follow-up pain scores for LLIF patients.