1 Division of Systems Biomedicine and Pharmacology, LACDR, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands. suruchi.bakshi@certara.com.
2 Certara QSP, 4818 SJ, Breda, The Netherlands. suruchi.bakshi@certara.com.
3 Cytokine, Chemokine and Complement DPU, Immunoinflammation TA Unit, GSK, Stevenage, UK.
4 Computational and Modelling Sciences, Platform Technology Sciences, GSK, Collegeville, Pennsylvania, USA.
5 Mathematical Institute, Leiden University, P.O. Box 9512, 2300 RA, Leiden, The Netherlands.
6 Clinical Pharmacology, Modelling and Simulation, GSK, Stevenage, UK.
7 Division of Systems Biomedicine and Pharmacology, LACDR, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands.