Low back pain (LBP) is a common disorder affecting an increasing number of people worldwide, whose diagnosis is focused on the identification of triggering causes. First line therapy usually starts from conservative approaches, whereas second line treatments include a spectrum of minimally invasive techniques, before resorting to more invasive surgical approaches. Among minimally invasive techniques, percutaneous oxygen-ozone injections represent one of the most common and cost-effective procedures. Aim of this study is to provide a metanalysis on literature evidences on percutaneous oxygen-ozone injections, comparing image-guided to non-image-guided techniques for LBP treatment. Imaging-guided procedures showed better performances compared to non-image-guided techniques based only on anatomical landmarks, with higher therapeutic efficacy and lower age-related variability in clinical results.
Keywords: BPI, Brief Pain Inventory; CT, Computed Tomography; Chemodiscolysis; DSA, Digital Subtraction Angiography; IF, Impact Factor; LBP, Low back pain; LDH, Lumbar Disc Hernia; Low back pain; Lumbar disc herniation; MRI, Magnetic Resonance Imaging; Meta-analysis; ODI, Oswestry Disability Index; PRISMA, Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines; Pain; Percutaneous oxygen-ozone injection; RMDQ, Roland Morris Disability Questionnaire; Sciatica; US, ultrasonography; VAS, Visual Analogue Scale for pain.
© 2021 The Authors. Published by Elsevier Ltd.