HLA typing data on 100 type 1 (insulin-dependent) diabetic patients from central Italy show a negative association with DR5 rather than with DR2

M Vela; D Adorno; A Longo; F Papola; D Maccarone; D Centis; M P Raponi; A Candela; L Campea; M Orsini

doi:10.1016/0090-1229(87)90121-8

HLA typing data on 100 type 1 (insulin-dependent) diabetic patients from central Italy show a negative association with DR5 rather than with DR2

Clin Immunol Immunopathol. 1987 Oct;45(1):143-6. doi: 10.1016/0090-1229(87)90121-8.

Authors

M Vela, D Adorno, A Longo, F Papola, D Maccarone, D Centis, M P Raponi, A Candela, L Campea, M Orsini, et al.

PMID: 3497749
DOI: 10.1016/0090-1229(87)90121-8

Abstract

HLA typing of 100 Type 1 diabetic patients from the Rome area confirmed the strong association with DR3 and DR4 and the prevalence of DR3/4 heterozygotes. However, DR5 rather than DR2 showed a significantly negative association.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Child
Child, Preschool
Diabetes Mellitus, Type 1 / immunology*
Female
HLA-D Antigens / analysis*
HLA-DR Antigens / analysis*
HLA-DR2 Antigen
HLA-DR3 Antigen
HLA-DR4 Antigen
HLA-DR5 Antigen
Humans
Italy
Male

Substances

HLA-D Antigens
HLA-DR Antigens
HLA-DR2 Antigen
HLA-DR3 Antigen
HLA-DR4 Antigen
HLA-DR5 Antigen