A Nationwide Evaluation of the Prevalence of Human Papillomavirus in Brazil (POP-Brazil Study): Protocol for Data Quality Assurance and Control

Jaqueline Driemeyer Correia Horvath; Marina Bessel; Natália Luiza Kops; Flávia Moreno Alves Souza; Gerson Mendes Pereira; Eliana Marcia Wendland

doi:10.2196/31365

A Nationwide Evaluation of the Prevalence of Human Papillomavirus in Brazil (POP-Brazil Study): Protocol for Data Quality Assurance and Control

JMIR Res Protoc. 2022 Jan 5;11(1):e31365. doi: 10.2196/31365.

Authors

Jaqueline Driemeyer Correia Horvath¹, Marina Bessel¹, Natália Luiza Kops¹, Flávia Moreno Alves Souza², Gerson Mendes Pereira², Eliana Marcia Wendland^{1

3}

Affiliations

¹ Escritório de Projetos, Programa de Apoio ao Desenvolvimento Institucional do Sistema Único de Saúde, Hospital Moinhos de Vento, Porto Alegre, Brazil.
² Department of Chronic Conditions Diseases and Sexually Transmitted Infections, Health Surveillance Secretariat, Ministry of Health, Brasília, Brazil.
³ Department of Community Health, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil.

PMID: 34989680
PMCID: PMC8771346
DOI: 10.2196/31365

Abstract

Background: The credibility of a study and its internal and external validity depend crucially on the quality of the data produced. An in-depth knowledge of quality control processes is essential as large and integrative epidemiological studies are increasingly prioritized.

Objective: This study aimed to describe the stages of quality control in the POP-Brazil study and to present an analysis of the quality indicators.

Methods: Quality assurance and control were initiated with the planning of this nationwide, multicentric study and continued through the development of the project. All quality control protocol strategies, such as training, protocol implementation, audits, and inspection, were discussed one by one. We highlight the importance of conducting a pilot study that provides the researcher the opportunity to refine or modify the research methodology and validating the results through double data entry, test-retest, and analysis of nonresponse rates.

Results: This cross-sectional, nationwide, multicentric study recruited 8628 sexually active young adults (16-25 years old) in 119 public health units between September 2016 and November 2017. The Human Research Ethics Committee of the Moinhos de Vento Hospital approved this project.

Conclusions: Quality control processes are a continuum, not restricted to a single event, and are fundamental to the success of data integrity and the minimization of bias in epidemiological studies. The quality control steps described can be used as a guide to implement evidence-based, valid, reliable, and useful procedures in most observational studies to ensure data integrity.

International registered report identifier (irrid): RR1-10.2196/31365.

Keywords: evidence-based medicine; quality assurance; quality control; quality data.

©Jaqueline Driemeyer Correia Horvath, Marina Bessel, Natália Luiza Kops, Flávia Moreno Alves Souza, Gerson Mendes Pereira, Eliana Marcia Wendland. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 05.01.2022.