Characteristics of the first 1119 SARS-CoV-2 Omicron variant cases, in Marseille, France, November-December 2021

J Med Virol. 2022 May;94(5):2290-2295. doi: 10.1002/jmv.27613. Epub 2022 Feb 3.

Abstract

One thousand one hundred and nineteen cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant cases have been diagnosed at the Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France, between November 28, 2021, and December 31, 2021. Among the 825 patients with known vaccination status, 383 (46.4%) were vaccinated, of whom 91.9% had received at least two doses of the vaccine. Interestingly, 26.3% of cases developed SARS-CoV-2 infection within 21 days following the last dose of vaccine suggesting possible early production of anti-SARS-CoV-2 facilitating antibodies. Twenty-one patients have been hospitalized, one patient required intensive care, and another patient who received a vaccine booster dose died.

Keywords: COVID-19; Delta; Intensive Care Unit; Omicron; SARS-CoV-2; coronavirus; death; hospitalization; infection; vaccination; variant.

MeSH terms

  • COVID-19 Vaccines
  • COVID-19* / epidemiology
  • France / epidemiology
  • Humans
  • SARS-CoV-2*

Substances

  • COVID-19 Vaccines

Supplementary concepts

  • SARS-CoV-2 variants