Clinical sign and symptom of primary vitreoretinal lymphoma short-time after retinal reattachment surgery: a case report

J Ophthalmic Inflamm Infect. 2022 Feb 5;12(1):6. doi: 10.1186/s12348-022-00283-5.

Abstract

Purpose: To describe a case of primary vitreoretinal lymphoma (PVRL), initially presented after successful repair of rhegmatogenous retinal detachment (RRD).

Case presentation: A 65-year-old man underwent pars plana vitrectomy with silicone oil tamponade for total RRD with grade C proliferative vitreoretinopathy in the right eye. Ten months after silicon oil removal, the patient presented with weakened vision, and multiple small yellow sub-retinal elevations was observed in fundus examination and optical coherence tomography (OCT). A cytopathologic examination of the vitreous showed lymphoid cell infiltration with nuclear atypia, which is strongly indicative of malignant lymphoma. Subretinal lesions continued with no noticeable improvement after 9 sessions of 400 microgram methotrexate therapy.

Conclusion: We identified the presentation of PVRL in a vitrectomized eye and the response to treatment in this article.

Keywords: Primary vitreoretinal lymphoma; Retinal detachment; Uveitis.

Publication types

  • Letter