Applying mucosal barrier injury laboratory-confirmed bloodstream infection criteria in patients with solid tumors and hematologic malignancies: A retrospective cohort study looking for the real source of infection

Ana Carolina Puin da Silva; Michely Fernandes Vieira; Maristela Pinheiro Freire; Lumena Vaz; Patrícia Rodrigues Bonazzi; Karim Yaqub Ibrahim; Maria Del Pilar Esteves Diz; Paulo Marcelo Hoff; Juliana Pereira; Vanderson Geraldo Rocha; Edson Abdala

doi:10.1017/ice.2021.466

Applying mucosal barrier injury laboratory-confirmed bloodstream infection criteria in patients with solid tumors and hematologic malignancies: A retrospective cohort study looking for the real source of infection

Infect Control Hosp Epidemiol. 2023 Feb;44(2):302-304. doi: 10.1017/ice.2021.466. Epub 2022 Feb 11.

Affiliations

¹ Hospital Infection Control and Infectious Diseases Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil.
² Oncology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil.
³ Hematology Service, Instituto do Cancer do Estado de Sao Paulo, School of Medicine, University of São Paulo, Brazil.
⁴ Department of Infectious and Parasitic Diseases, School of Medicine, University of São Paulo, Brazil.

PMID: 35144717
DOI: 10.1017/ice.2021.466

Abstract

We evaluated the interference of the mucosal barrier injury (MBI) laboratory-confirmed bloodstream infection (MBI-LCBI) criteria on the central-line-associated bloodstream infection (CLABSI) incidence density, and the proportion of catheter-related bloodstream infections (CRBSIs) among those classified as MBI. We detected 339 CLABSIs: 15.0% were classified as MBI-LCBIs, and among these, 19.6% were classified as CRBSIs.

MeSH terms

Catheter-Related Infections* / diagnosis
Catheter-Related Infections* / epidemiology
Catheterization, Central Venous* / adverse effects
Central Venous Catheters*
Communicable Diseases*
Hematologic Neoplasms* / complications
Humans
Neoplasms*
Retrospective Studies
Sepsis* / epidemiology