Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury

Joshua K Wong; Günther Deuschl; Robin Wolke; Hagai Bergman; Muthuraman Muthuraman; Sergiu Groppa; Sameer A Sheth; Helen M Bronte-Stewart; Kevin B Wilkins; Matthew N Petrucci; Emilia Lambert; Yasmine Kehnemouyi; Philip A Starr; Simon Little; Juan Anso; Ro'ee Gilron; Lawrence Poree; Giridhar P Kalamangalam; Gregory A Worrell; Kai J Miller; Nicholas D Schiff; Christopher R Butson; Jaimie M Henderson; Jack W Judy; Adolfo Ramirez-Zamora; Kelly D Foote; Peter A Silburn; Luming Li; Genko Oyama; Hikaru Kamo; Satoko Sekimoto; Nobutaka Hattori; James J Giordano; Diane DiEuliis; John R Shook; Darin D Doughtery; Alik S Widge; Helen S Mayberg; Jungho Cha; Kisueng Choi; Stephen Heisig; Mosadolu Obatusin; Enrico Opri; Scott B Kaufman; Prasad Shirvalkar; Christopher J Rozell; Sankaraleengam Alagapan; Robert S Raike; Hemant Bokil; David Green; Michael S Okun

doi:10.3389/fnhum.2022.813387

Proceedings of the Ninth Annual Deep Brain Stimulation Think Tank: Advances in Cutting Edge Technologies, Artificial Intelligence, Neuromodulation, Neuroethics, Pain, Interventional Psychiatry, Epilepsy, and Traumatic Brain Injury

Front Hum Neurosci. 2022 Mar 4:16:813387. doi: 10.3389/fnhum.2022.813387. eCollection 2022.

Authors

Joshua K Wong¹, Günther Deuschl², Robin Wolke², Hagai Bergman³, Muthuraman Muthuraman⁴, Sergiu Groppa⁴, Sameer A Sheth⁵, Helen M Bronte-Stewart⁶, Kevin B Wilkins⁶, Matthew N Petrucci⁶, Emilia Lambert⁶, Yasmine Kehnemouyi⁶, Philip A Starr⁷, Simon Little⁷, Juan Anso⁷, Ro'ee Gilron⁷, Lawrence Poree⁸, Giridhar P Kalamangalam⁹, Gregory A Worrell¹⁰, Kai J Miller¹¹, Nicholas D Schiff¹², Christopher R Butson¹, Jaimie M Henderson¹³, Jack W Judy¹⁴, Adolfo Ramirez-Zamora¹, Kelly D Foote¹⁵, Peter A Silburn¹⁶, Luming Li¹⁷, Genko Oyama¹⁸, Hikaru Kamo¹⁸, Satoko Sekimoto¹⁸, Nobutaka Hattori¹⁸, James J Giordano¹⁹, Diane DiEuliis²⁰, John R Shook²¹, Darin D Doughtery²², Alik S Widge²³, Helen S Mayberg²⁴, Jungho Cha²⁴, Kisueng Choi²⁴, Stephen Heisig²⁴, Mosadolu Obatusin²⁴, Enrico Opri²⁵, Scott B Kaufman²⁶, Prasad Shirvalkar^{6

27}, Christopher J Rozell²⁸, Sankaraleengam Alagapan²⁸, Robert S Raike²⁹, Hemant Bokil³⁰, David Green³¹, Michael S Okun¹

Affiliations

¹ Department of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
² Department of Neurology, Christian-Albrechts-University, Kiel, Germany.
³ Department of Medical Neurobiology (Physiology), Institute of Medical Research Israel-Canada, Hebrew University of Jerusalem, Jerusalem, Israel.
⁴ Biomedical Statistics and Multimodal Signal Processing Unit, Section of Movement Disorders and Neurostimulation, Focus Program Translational Neuroscience, Department of Neurology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
⁵ Department of Neurological Surgery, Baylor College of Medicine, Houston, TX, United States.
⁶ The Human Motor Control and Neuromodulation Laboratory, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford University, Stanford, CA, United States.
⁷ Department of Neurological Surgery, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, United States.
⁸ Department of Anesthesia, University of California, San Francisco, San Francisco, CA, United States.
⁹ Department of Neurology, Wilder Center for Epilepsy Research, University of Florida, Gainesville, FL, United States.
¹⁰ Department of Neurology, Mayo Clinic, Rochester, NY, United States.
¹¹ Department of Neurosurgery, Mayo Clinic, Rochester, NY, United States.
¹² Department of Neurology, Weill Cornell Brain and Spine Institute, Weill Cornell Medicine, New York, NY, United States.
¹³ Department of Neurosurgery, Stanford University, Stanford, CA, United States.
¹⁴ Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL, United States.
¹⁵ Department of Neurosurgery, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, United States.
¹⁶ Queensland Brain Institute, University of Queensland and Saint Andrews War Memorial Hospital, Brisbane, QLD, Australia.
¹⁷ National Engineering Laboratory for Neuromodulation, School of Aerospace Engineering, Tsinghua University, Beijing, China.
¹⁸ Department of Neurology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
¹⁹ Neuroethics Studies Program, Department of Neurology, Georgetown University Medical Center, Washington, DC, United States.
²⁰ US Department of Defense Fort Lesley J. McNair, National Defense University, Washington, DC, United States.
²¹ Department of Philosophy and Science Education, University of Buffalo, Buffalo, NY, United States.
²² Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
²³ Department of Psychiatry, University of Minnesota, Minneapolis, MN, United States.
²⁴ Department of Neurology and Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
²⁵ Department of Neurology, Emory University, Atlanta, GA, United States.
²⁶ Department of Psychology, Columbia University, New York, NY, United States.
²⁷ Department of Anesthesiology (Pain Management) and Neurology, University of California, San Francisco, San Francisco, CA, United States.
²⁸ School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, United States.
²⁹ Restorative Therapies Group Implantables, Research and Core Technology, Medtronic Inc., Minneapolis, MN, United States.
³⁰ Boston Scientific Neuromodulation Corporation, Valencia, CA, United States.
³¹ NeuroPace, Inc., Mountain View, CA, United States.

Abstract

DBS Think Tank IX was held on August 25-27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers (from industry and academia) can freely discuss current and emerging deep brain stimulation (DBS) technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year's meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury.

Keywords: adaptive DBS; artificial intelligence; deep brain stimulation; epilepsy; interventional psychiatry; neuroethics; pain; traumatic brain injury.

Copyright © 2022 Wong, Deuschl, Wolke, Bergman, Muthuraman, Groppa, Sheth, Bronte-Stewart, Wilkins, Petrucci, Lambert, Kehnemouyi, Starr, Little, Anso, Gilron, Poree, Kalamangalam, Worrell, Miller, Schiff, Butson, Henderson, Judy, Ramirez-Zamora, Foote, Silburn, Li, Oyama, Kamo, Sekimoto, Hattori, Giordano, DiEuliis, Shook, Doughtery, Widge, Mayberg, Cha, Choi, Heisig, Obatusin, Opri, Kaufman, Shirvalkar, Rozell, Alagapan, Raike, Bokil, Green and Okun.

Abstract

Grants and funding