On 'Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?' by Graham W. Burton, Anne Joyce, Keith U. Ingold

Arch Biochem Biophys. 2022 Sep 15:726:109195. doi: 10.1016/j.abb.2022.109195. Epub 2022 Mar 28.

Abstract

Application of a time-tested quantitative method of measuring peroxyl radical production in conjunction with the determination of the stoichiometry of the reaction of peroxyl radicals with α-tocopherol has permitted the conclusion that α-tocopherol is the major lipid-soluble chain-breaking antioxidant in human plasma and red cell membranes.

MeSH terms

  • Antioxidants* / metabolism
  • Erythrocyte Membrane / metabolism
  • Free Radicals / metabolism
  • Humans
  • Lipid Peroxidation
  • Lipids
  • Plasma
  • Vitamin E*
  • alpha-Tocopherol

Substances

  • Antioxidants
  • Free Radicals
  • Lipids
  • Vitamin E
  • alpha-Tocopherol