Metabolic Acidosis: Differentiating the Causes in the Poisoned Patient

Bryan S Judge

doi:10.1016/j.emc.2022.01.002

Metabolic Acidosis: Differentiating the Causes in the Poisoned Patient

Emerg Med Clin North Am. 2022 May;40(2):251-264. doi: 10.1016/j.emc.2022.01.002. Epub 2022 Apr 5.

Author

Bryan S Judge¹

Affiliation

¹ Department of Emergency Medicine, Division of Medical Toxicology, Michigan State University College of Human Medicine, 15 Michigan Ave NE, Grand Rapids, MI 49503, USA; Spectrum Health Butterworth Emergency Department MC 49, 100 Michigan NE, Grand Rapids, MI 49503, USA. Electronic address: bryan.judge@spectrumhealth.org.

PMID: 35461622
DOI: 10.1016/j.emc.2022.01.002

Abstract

Numerous drugs and toxins can cause metabolic acidosis. The treating clinician should be aware of the many compounds that can produce metabolic acidosis following an accidental exposure, an overdose, or with therapeutic use. Awareness and comprehension of those substances associated with metabolic acidosis will facilitate the diagnosis and treatment of poisoned patients.

Keywords: Drugs; Metabolic acidosis; Overdose; Poisoned patients; Toxins.

Publication types

Review

MeSH terms

Acidosis* / chemically induced
Acidosis* / diagnosis
Causality
Drug Overdose* / diagnosis
Drug Overdose* / therapy
Humans
Poisons* / therapeutic use

Substances

Poisons