How to Treat Breast Cancer After Childhood Cancer: Management of Oncologic and Cardiovascular Concerns

Anne H Blaes; Suma Konety; Jane Hui; Kathryn Dusenbery; Jianling Yuan; Susan Dent; Kevin C Oeffinger; Lucie M Turcotte

doi:10.1016/j.jaccao.2021.12.003

How to Treat Breast Cancer After Childhood Cancer: Management of Oncologic and Cardiovascular Concerns

JACC CardioOncol. 2022 Mar 15;4(1):126-129. doi: 10.1016/j.jaccao.2021.12.003. eCollection 2022 Mar.

Authors

Anne H Blaes^{1

2}, Suma Konety³, Jane Hui^{2

4}, Kathryn Dusenbery⁵, Jianling Yuan⁵, Susan Dent⁶, Kevin C Oeffinger⁶, Lucie M Turcotte^{2

7}

Affiliations

¹ Division of Hematology/Oncology, University of Minnesota, Minneapolis, Minnesota, USA.
² University of Minnesota, Masonic Cancer Center, Minneapolis, Minnesota, USA.
³ Division of Cardiology, University of Minnesota, Minneapolis, Minnesota, USA.
⁴ Division of Surgical Oncology, University of Minnesota, Minneapolis, Minnesota, USA.
⁵ Department of Radiation Oncology, University of Minnesota, Minneapolis, Minnesota, USA.
⁶ Duke University, Duke Cancer Institute, Raleigh, North Carolina, USA.
⁷ Division of Pediatric Oncology, University of Minnesota, Minneapolis, Minnesota, USA.

Abstract

•Childhood cancer survivors are at higher risk for the development of breast cancer necessitating early breast cancer screening, often with both breast MRI and mammography.•Risk-stratify breast cancer treatment, taking into account prior radiation fields, surgical procedures, use of anthracyclines, and current comorbidities is essential.•Aggressive management of CV risk factors in collaboration with cardiologists, oncologists, primary care providers, and allied health care providers is needed to provide the best cancer treatment while optimizing CV health.

Keywords: cancer survivorship; coronary artery disease; heart failure.

Publication types

Review

Grants and funding

K08 CA234232/CA/NCI NIH HHS/United States