cDCDD-NRP is consistent with US legal standards for determining death

Am J Transplant. 2022 Oct;22(10):2302-2305. doi: 10.1111/ajt.17083. Epub 2022 May 18.

Abstract

Donation after circulatory determination of death (DCDD) has increased organ donation rates in the US over the past decade within an established legal framework, which is consistent with and supports individual and family decisions regarding organ donation in the context of end-of-life care. A new application, controlled DCDD donation utilizing thoracoabdominal normothermic regional perfusion (NRP) protocols (cDCDD-NRP), provides the opportunity to maximize a donation decision by recovering additional organs for transplant, including the heart, and to limit the detrimental impact of warm ischemic time by perfusing organs in situ following the declaration of circulatory death. In this viewpoint, we narrate our rationale for why cDCDD-NRP is consistent within the existing legal framework for organ donation in the United States and recommend no changes to the Uniform Determination of Death Act.

Keywords: Uniform Anatomical Gift Act; Uniform Determination of Death Act; controlled donation after circulatory determination of death; donation after circulatory determination of death; normothermic regional perfusion.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Death
  • Humans
  • Organ Preservation* / methods
  • Perfusion / methods
  • Tissue Donors
  • Tissue and Organ Procurement*
  • United States