Chest wall reconstruction for deep radiation necrosis: case report and overview of surgical options

Acta Chir Belg. 2023 Oct;123(5):566-572. doi: 10.1080/00015458.2022.2076026. Epub 2022 May 22.

Abstract

Introduction: To report a case of radiation necrosis after reirradiation for breast cancer and the difficulties encountered when treating these complex cases.

Patients and methods: We present an 86-year-old woman with a history of right-sided intraductal breast cancer treated with a right mastectomy followed by local adjuvant radiotherapy (50 Gray). Twelve years later, she was diagnosed with a local recurrence in the mastectomy scar which was treated with local resection (including resection of rib four) and adjuvant radiotherapy up to 32 Gray. In July 2020 she presents at the Department of Plastic and Reconstructive Surgery with a chronic ulcer on the right-sided hemithorax.

Results: A multi-staged, multidisciplinary approach was necessary to secure lasting coverage of the extensive defect.

Conclusion: Thoracic radiation necrosis should be subject to a multidisciplinary approach (plastic and thoracic surgeons) pre-, per-, and post-operatively. Each case may require a different surgical approach depending on the size and depth of the defect, patients' age, comorbidities, and previous medical treatment.

Keywords: Breast cancer; chest wall reconstruction; radiation necrosis; radiotherapy; reconstructive surgery.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Breast Neoplasms* / radiotherapy
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Mastectomy
  • Necrosis / etiology
  • Necrosis / surgery
  • Radiation Injuries* / etiology
  • Radiation Injuries* / surgery
  • Thoracic Wall* / radiation effects
  • Thoracic Wall* / surgery