Iron Speciation and Iron Binding Proteins in Arthrospira platensis Grown in Media Containing Different Iron Concentrations

Int J Mol Sci. 2022 Jun 3;23(11):6283. doi: 10.3390/ijms23116283.

Abstract

Cyanobacteria are characterized by high iron content. This study investigated the effects of varying iron concentrations (1, 5, and 10 mg L-1) in the culture media on the biochemical composition and the iron bioaccumulation and speciation in Arthrospira platensis F&M-C256. Iron content measured in biomasses varied from 0.35 to 2.34 mg g-1 dry weight depending on the iron concentration in the culture media. These biomasses can be considered of interest for the production of spirulina-based supplements with low and high iron content. Iron speciation was studied using size exclusion chromatography followed by atomic absorption spectrometry and proteomic analysis. The role of C-phycocyanin as an iron binding protein was also investigated. Overall, the present results provide a better understanding of iron metabolism in cyanobacteria and a foundation for further studies.

Keywords: Arthrospira platensis; culture media; cyanobacteria; iron bioaccumulation; iron speciation.

MeSH terms

  • Culture Media / metabolism
  • Iron / metabolism
  • Iron-Binding Proteins / metabolism
  • Proteomics
  • Spirulina* / chemistry

Substances

  • Culture Media
  • Iron-Binding Proteins
  • Iron

Supplementary concepts

  • Arthrospira platensis

Grants and funding

This research received no external funding.