Progress in Gastroparesis - A Narrative Review of the Work of the Gastroparesis Clinical Research Consortium

Pankaj J Pasricha; Madhusudan Grover; Katherine P Yates; Thomas L Abell; Kenneth L Koch; Richard W McCallum; Irene Sarosiek; Cheryl E Bernard; Braden Kuo; Robert Bulat; Robert J Shulman; Bruno P Chumpitazi; James Tonascia; Laura A Miriel; Laura A Wilson; Mark L Van Natta; Emily Mitchell; Frank Hamilton; Gianrico Farrugia; Henry P Parkman; NIDDK/NIH GpCRC consortium

doi:10.1016/j.cgh.2022.05.022

Progress in Gastroparesis - A Narrative Review of the Work of the Gastroparesis Clinical Research Consortium

Clin Gastroenterol Hepatol. 2022 Dec;20(12):2684-2695.e3. doi: 10.1016/j.cgh.2022.05.022. Epub 2022 Jun 7.

Authors

Pankaj J Pasricha¹, Madhusudan Grover², Katherine P Yates³, Thomas L Abell⁴, Kenneth L Koch⁵, Richard W McCallum⁶, Irene Sarosiek⁶, Cheryl E Bernard², Braden Kuo⁷, Robert Bulat⁸, Robert J Shulman⁹, Bruno P Chumpitazi⁹, James Tonascia³, Laura A Miriel³, Laura A Wilson³, Mark L Van Natta³, Emily Mitchell³, Frank Hamilton¹⁰, Gianrico Farrugia², Henry P Parkman¹¹; NIDDK/NIH GpCRC consortium

Affiliations

¹ Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: pasricha@jhu.edu.
² Mayo Clinic, Rochester, Minnesota.
³ Johns Hopkins University, Baltimore, Maryland.
⁴ University of Louisville, Louisville, Kentucky.
⁵ Wake Forest University, Winston-Salem, North Carolina.
⁶ Texas Tech University, El Paso, Texas.
⁷ Massachusetts General Hospital, Boston, Massachusetts.
⁸ Johns Hopkins University School of Medicine, Baltimore, Maryland.
⁹ Baylor College of Medicine, Houston, Texas.
¹⁰ National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
¹¹ Temple University, Philadelphia, Pennsylvania.

Abstract

The Gastroparesis Clinical Research Consortium is a multicenter coalition created and funded by the National Institutes of Diabetes and Digestive and Kidney Disorders, with a mission to advance understanding of the pathophysiology of gastroparesis and develop an effective treatment for patients with symptomatic gastroparesis. In this review, we summarize the results of the published Gastroparesis Clinical Research Consortium studies as a ready and convenient resource for gastroenterologists and others to provide a clear understanding of the consortium's experience and perspective on gastroparesis and related disorders.

Keywords: Clinical Trials; Functional Dyspepsia; Gastroparesis; Motility Disorders.

Publication types

Review
Research Support, N.I.H., Extramural

MeSH terms

Gastric Emptying
Gastroparesis* / drug therapy
Humans
Multicenter Studies as Topic
Treatment Outcome

Abstract

Publication types

MeSH terms

Grants and funding