Contemporary Management of Refractory Angina

Rebekah Lantz; Odayme Quesada; Georgia Mattingly; Timothy D Henry

doi:10.1016/j.iccl.2022.03.002

Contemporary Management of Refractory Angina

Interv Cardiol Clin. 2022 Jul;11(3):279-292. doi: 10.1016/j.iccl.2022.03.002.

Authors

Rebekah Lantz¹, Odayme Quesada², Georgia Mattingly¹, Timothy D Henry³

Affiliations

¹ The Lindner Research Center at the Christ Hospital, 2123 Auburn Avenue, Suite 424, Cincinnati, OH 45219, USA.
² Women's Heart Program at The Christ Hospital, 2123 Auburn Avenue, Suite 424, Cincinnati, OH 45219, USA. Electronic address: https://twitter.com/Odayme.
³ The Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, 2123 Auburn Avenue, Suite 424, Cincinnati, OH 45219, USA. Electronic address: Tim.Henry@thechristhospital.com.

Abstract

Refractory angina (RA) is defined as chest pain caused by coronary ischemia in patients on maximal medical therapy and is not amenable to revascularization despite advanced coronary artery disease (CAD). The long-term prognosis has improved with optimal medical therapy including risk factor modification. Still, patients are left with major impairment in quality of life and have high resource utilization with limited treatment options. We review the novel invasive and noninvasive therapies under investigation for RA.

Keywords: Angina; Coronary artery disease; Microvascular.

Publication types

Review
Research Support, N.I.H., Extramural

MeSH terms

Angina Pectoris / diagnosis
Angina Pectoris / therapy
Coronary Artery Disease* / complications
Coronary Artery Disease* / surgery
Humans
Myocardial Ischemia*
Quality of Life
Risk Factors

Grants and funding

K23 HL151867/HL/NHLBI NIH HHS/United States