Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

Acta Pharmacol Sin. 2023 Jan;44(1):255-257. doi: 10.1038/s41401-022-00929-z. Epub 2022 Jun 30.

Xiao-Dong Luan^#^{1

2

3}, Bin-Xian Chen^#^{1

2}, Wei-Juan Shang^#⁴, Wan-Chao Yin⁵, Ye Jin², Lei-Ke Zhang^#⁶, H Eric Xu^#^{7

8}, Shu-Yang Zhang^#^{9

10

11}

¹ School of Medicine, Tsinghua University, Haidian District, Beijing, 100084, China.
² Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
³ Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China.
⁴ State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
⁵ The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
⁶ State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China. zhangleike@wh.iov.cn.
⁷ The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. eric.xu@simm.ac.cn.
⁸ University of Chinese Academy of Sciences, Beijing, 100049, China. eric.xu@simm.ac.cn.
⁹ School of Medicine, Tsinghua University, Haidian District, Beijing, 100084, China. shuyangzhang103@nrdrs.org.
¹⁰ Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China. shuyangzhang103@nrdrs.org.
¹¹ Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing, 100084, China. shuyangzhang103@nrdrs.org.

^# Contributed equally.

No abstract available

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