Use of systematic evidence maps within the US environmental protection agency (EPA) integrated risk information system (IRIS) program: Advancements to date and looking ahead

Kristina A Thayer; Rachel M Shaffer; Michelle Angrish; Xabier Arzuaga; Laura M Carlson; Allen Davis; Laura Dishaw; Ingrid Druwe; Catherine Gibbons; Barbara Glenn; Ryan Jones; J Phillip Kaiser; Channa Keshava; Nagalakshmi Keshava; Andrew Kraft; Lucina Lizarraga; Kristan Markey; Amanda Persad; Elizabeth G Radke; Glenn Rice; Brittany Schulz; Teresa Shannon; Andrew Shapiro; Shane Thacker; Suryanarayana Vulimiri; George Woodall; Erin Yost

doi:10.1016/j.envint.2022.107363

Use of systematic evidence maps within the US environmental protection agency (EPA) integrated risk information system (IRIS) program: Advancements to date and looking ahead

Environ Int. 2022 Nov:169:107363. doi: 10.1016/j.envint.2022.107363. Epub 2022 Aug 31.

Authors

Kristina A Thayer¹, Rachel M Shaffer², Michelle Angrish³, Xabier Arzuaga⁴, Laura M Carlson⁵, Allen Davis⁶, Laura Dishaw⁷, Ingrid Druwe⁸, Catherine Gibbons⁹, Barbara Glenn¹⁰, Ryan Jones¹¹, J Phillip Kaiser¹², Channa Keshava¹³, Nagalakshmi Keshava¹⁴, Andrew Kraft¹⁵, Lucina Lizarraga¹⁶, Kristan Markey¹⁷, Amanda Persad¹⁸, Elizabeth G Radke¹⁹, Glenn Rice²⁰, Brittany Schulz²¹, Teresa Shannon²², Andrew Shapiro²³, Shane Thacker²⁴, Suryanarayana Vulimiri²⁵, George Woodall²⁶, Erin Yost²⁷

Affiliations

¹ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: thayer.kris@epa.gov.
² Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: shaffer.rachel@epa.gov.
³ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: angrish.michelle@epa.gov.
⁴ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Arzuaga.Xabier@epa.gov.
⁵ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: Carlson.Laura@epa.gov.
⁶ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Davis.Allen@epa.gov.
⁷ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Dishaw.Laura@epa.gov.
⁸ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Druwe.Ingrid@epa.gov.
⁹ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Gibbons.Catherine@epa.gov.
¹⁰ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Glenn.Barbara@epa.gov.
¹¹ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: Jones.Ryan@epa.gov.
¹² Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Kaiser.Jonathan-Phillip@epa.gov.
¹³ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Keshava.Channa@epa.gov.
¹⁴ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: keshava.nagu@epa.gov.
¹⁵ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: kraft.andrew@epa.gov.
¹⁶ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: lizarraga.lucina@epa.gov.
¹⁷ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: markey.kristan@epa.gov.
¹⁸ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: persad.Amanda@epa.gov.
¹⁹ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: radke-farabaugh.elizabeth@epa.gov.
²⁰ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: rice.glenn@epa.gov.
²¹ Oak Ridge Associated Universities, TN, USA. Electronic address: schulz.brittany@epa.gov.
²² Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Shannon.Teresa@epa.gov.
²³ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: Shapiro.Andy@epa.gov.
²⁴ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: Thacker.Samuel@epa.gov.
²⁵ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA. Electronic address: Vulimiri.Sury@epa.gov.
²⁶ Center for Public Health and Environmental Assessment, Health & Environmental Effects Assessment Division, US EPA, NC, USA. Electronic address: Woodall.George@epa.gov.
²⁷ Center for Public Health and Environmental Assessment, Chemical & Pollutant Assessment Division, US EPA, NC, USA.

PMID: 36057470
DOI: 10.1016/j.envint.2022.107363

Abstract

Systematic evidence maps (SEMs) are increasingly used to inform decision-making and risk management priority-setting and to serve as problem formulation tools to refine the focus of questions that get addressed in full systematic reviews. Within the U.S. Environmental Protection Agency (EPA) Office of Research and Development (ORD) Integrated Risk Information System (IRIS), SEMs have been used to inform data gaps, determine the need for updated assessments, inform assessment priorities, and inform development of study evaluation considerations, among other uses. Increased utilization of SEMs across the environmental health field has the potential to increase transparency and efficiency for data gathering, problem formulation, read-across, and evidence surveillance. Use of the SEM templates published in the companion text (Thayer et al.) can promote harmonization in the environmental health community and create more opportunities for sharing extracted content.

Keywords: Hazard characterization; Risk assessment; Scoping review; Systematic review; Toxicity.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Environmental Health*
Information Systems
Risk Assessment
Risk Management*
United States
United States Environmental Protection Agency