Rectal linitis plastica as the first presentation of metastatic lobular breast cancer: an endoscopic ultrasound diagnosis

Clin J Gastroenterol. 2022 Dec;15(6):1072-1077. doi: 10.1007/s12328-022-01690-w. Epub 2022 Sep 13.

Abstract

Gastrointestinal tract is an uncommon site of breast cancer metastasis. Rectal linitis plastica (RLP) is a rare presentation of rectal neoplasia, both primary and secondary, and refers to a diffuse infiltration of the wall by an infiltrating carcinoma. Diagnostic assessment of RLP may be challenging since cross-sectional imaging and endoscopic findings may be nonspecific, and endoscopic biopsies are frequently non-diagnostic due to the submucosal disease localization. Endoscopic ultrasound (EUS) with fine needle biopsy (FNB) is widely used for the diagnostic assessment of sub-epithelial lesions of upper and lower gastrointestinal tract. However, data about the use of EUS in case of rectal linitis plastica are very poor. We present a case of rectal metastasis as the first presentation of lobular breast cancer, presenting as rectal linitis plastica and diagnosed with EUS-FNB.

Keywords: Endoscopic ultrasound; Lobular breast cancer; Rectal linitis plastica; Rectal metastasis.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Fine-Needle
  • Breast Neoplasms* / diagnostic imaging
  • Breast Neoplasms* / pathology
  • Carcinoma, Lobular* / diagnostic imaging
  • Carcinoma, Lobular* / secondary
  • Female
  • Humans
  • Linitis Plastica* / diagnostic imaging
  • Linitis Plastica* / pathology
  • Rectal Neoplasms* / diagnostic imaging
  • Rectal Neoplasms* / pathology
  • Stomach Neoplasms* / pathology