Distinct immune-response profile of Richter transformation chronic lymphocytic leukemia (CLL), defined by high expression of PD1, LAG3, TIM3 and IL-10

Leuk Lymphoma. 2022 Dec;63(13):3222-3226. doi: 10.1080/10428194.2022.2123236. Epub 2022 Sep 14.

Authors

Amir Behdad^{1

2}, Matthew John Schipma³, Shuo Ma², Yi-Hua Chen¹, Qing Ching Chen¹

Affiliations

¹ Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
² Department of Medicine (Hematology and Oncology), Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
³ Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

PMID: 36102789
DOI: 10.1080/10428194.2022.2123236

No abstract available

MeSH terms

Cell Transformation, Neoplastic / genetics
Hepatitis A Virus Cellular Receptor 2 / genetics
Humans
Interleukin-10 / genetics
Leukemia, Lymphocytic, Chronic, B-Cell* / genetics
Lymphoma, Large B-Cell, Diffuse*

Substances

Hepatitis A Virus Cellular Receptor 2
Interleukin-10