Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999

Franck Rapaport; Kenneth Seier; Yaseswini Neelamraju; Duane Hassane; Timour Baslan; Daniel T Gildea; Samuel Haddox; Tak Lee; H Moses Murdock; Caroline Sheridan; Alexis Thurmond; Ling Wang; Martin Carroll; Larry D Cripe; Hugo Fernandez; Christopher E Mason; Elisabeth Paietta; Gail J Roboz; Zhuoxin Sun; Martin S Tallman; Yanming Zhang; Mithat Gönen; Ross Levine; Ari M Melnick; Maria Kleppe; Francine E Garrett-Bakelman

doi:10.1038/s41408-022-00736-z

Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999

Blood Cancer J. 2022 Sep 23;12(9):137. doi: 10.1038/s41408-022-00736-z.

Authors

Franck Rapaport^#^{1

2}, Kenneth Seier^#³, Yaseswini Neelamraju^#⁴, Duane Hassane⁵, Timour Baslan⁶, Daniel T Gildea⁴, Samuel Haddox⁴, Tak Lee⁵, H Moses Murdock⁷, Caroline Sheridan⁵, Alexis Thurmond⁴, Ling Wang⁵, Martin Carroll⁷, Larry D Cripe⁸, Hugo Fernandez⁹, Christopher E Mason^{10

11

12}, Elisabeth Paietta¹³, Gail J Roboz¹⁴, Zhuoxin Sun¹⁵, Martin S Tallman¹⁶, Yanming Zhang¹⁷, Mithat Gönen^#³, Ross Levine^#¹, Ari M Melnick^#⁵, Maria Kleppe^#¹, Francine E Garrett-Bakelman^#^{18

19

20

21}

Affiliations

¹ Human Oncology and Pathogenesis Program, Molecular Cancer Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
² Center for Clinical and Translational Science, The Rockefeller University, New York, NY, USA.
³ Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
⁴ Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA.
⁵ Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
⁶ Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
⁷ Division of Hematology and Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
⁸ Simon Cancer Center, Indiana University, Indianapolis, IN, USA.
⁹ Department of Malignant Hematology & Cellular Therapy, Moffitt Cancer Center, Tampa, FL, USA.
¹⁰ Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
¹¹ Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
¹² The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, USA.
¹³ Montefiore Medical Center, Bronx, NY, USA.
¹⁴ Weill Cornell Medicine and The New York Presbyterian Hospital, New York, NY, USA.
¹⁵ Dana-Farber Cancer Institute, Boston, MA, USA.
¹⁶ Memorial Sloan Kettering Cancer Center, New York, NY, USA.
¹⁷ Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
¹⁸ Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA. fg5q@virginia.edu.
¹⁹ Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA. fg5q@virginia.edu.
²⁰ Department of Medicine, University of Virginia, Charlottesville, VA, USA. fg5q@virginia.edu.
²¹ University of Virginia Cancer Center, Charlottesville, VA, USA. fg5q@virginia.edu.

^# Contributed equally.

Abstract

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Female
Humans
Leukemia, Myeloid, Acute* / diagnosis
Leukemia, Myeloid, Acute* / drug therapy
Leukemia, Myeloid, Acute* / genetics

Abstract

Publication types

MeSH terms

Grants and funding