Clinical and immunological analysis of a large kindred affected by autoimmune lymphoproliferative syndrome (ALPS) due to a novel TNFRSF6 mutation displaying age dependent disease activity

Affiliations

• ¹ Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, Brescia, Italy.
• ² Pediatric Oncohematology and Bone Marrow Transplant (BMT) Unit, Children's Hospital, Spedali Civili, Brescia, Italy.
• ³ Flow Cytometry Laboratory, Diagnostic Department, ASST Spedali Civili, Brescia, Italy.
• ⁴ Medical Genetics Laboratory, ASST-Spedali Civili, Brescia, Italy.
• ⁵ Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, Department of Clinical and Experimental Sciences, University of Brescia and ASST-Spedali Civili of Brescia, Brescia, Italy. Electronic address: vlougarisbs@yahoo.com.