The risk of questioning the safety of drugs considered safe in pregnancy at the era of big data: the everlasting case of doxylamine

Affiliations

• ¹ Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland; Service of Pharmacy, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. Electronic address: Alice.Panchaudmonnat@biham.unibe.ch.
• ² School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, The Rotunda Hospital, Dublin, Ireland.
• ³ Charité - Universitätsmedizin Berlin, Pharmakovigilanzzentrum Embryonaltoxikologie, Institut für Klinische Pharmakologie und Toxikologie, Berlin, Germany.
• ⁴ The Israeli Teratology Information Service, Ministry of Health, Jerusalem, Israel.
• ⁵ Clinical Genetics Unit, Department of Women's and Children's Health, University of Padova, Padova, Italy.
• ⁶ The Israeli Teratology Information Service, Ministry of Health, Jerusalem, Israel; The Hebrew University Hadassah Medical School, Jerusalem, Israel.
• ⁷ Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.