Physiological Monitoring in Patients with Acute Brain Injury: A Multimodal Approach

Tracey H Fan; Eric S Rosenthal

doi:10.1016/j.ccc.2022.06.006

Physiological Monitoring in Patients with Acute Brain Injury: A Multimodal Approach

Crit Care Clin. 2023 Jan;39(1):221-233. doi: 10.1016/j.ccc.2022.06.006. Epub 2022 Sep 29.

Authors

Tracey H Fan¹, Eric S Rosenthal²

Affiliations

¹ Department of Neurology, Division of Neurocritical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02493, USA; Department of Neurology, Division of Neurocritical Care, Brigham and Women's Hospital, 55 Fruit Street, Boston, MA 02493, USA.
² Department of Neurology, Division of Neurocritical Care, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02493, USA; Department of Neurology, Division of Clinical Neurophysiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02493, USA. Electronic address: erosenthal@mgh.harvard.edu.

PMID: 36333033
DOI: 10.1016/j.ccc.2022.06.006

Abstract

Neurocritical care management of acute brain injury (ABI) is focused on identification, prevention, and management of secondary brain injury (SBI). Physiologic monitoring of the brain and other organ systems has a role to predict patient recovery or deterioration, guide individualized therapeutic interventions, and measure response to treatment, with the goal of improving patient outcomes. In this review, we detail how specific physiologic markers of brain injury and neuromonitoring tools are integrated and used in ABI patients to develop therapeutic approaches to prevent SBI.

Keywords: Acute brain injury; Multimodal monitoring; Neuromonitoring; Secondary brain injury; Subarachnoid hemorrhage; Traumatic brain injury.

Publication types

Review

MeSH terms

Brain
Brain Injuries* / therapy
Critical Care*
Humans
Monitoring, Physiologic

Grants and funding

K23 NS105950/NS/NINDS NIH HHS/United States