A Rare Case of Collision Tumours of the Ovary: An Ovarian Serous Cystadenoma Coexisting with Fibrothecoma

Diagnostics (Basel). 2022 Nov 17;12(11):2840. doi: 10.3390/diagnostics12112840.

Abstract

The incidence of epithelial tumours of the ovary ranges from 9-17 per 100,000 and is the highest in high-income countries, with the exception of the Japan. The coexistence of neoplastic Müllerian epithelial and sex cord-stromal elements within a single tumour is extremely rare. We describe the case of a 74-year-old woman with a voluminous left adnexal formation. Pre-operative assessment with ultrasound evaluation made a suspicious diagnosis of benignity of the lesion. Bilateral salpingo-ovariectomy was performed. Intraoperative frozen section analysis results in the diagnosis of fibrothecoma in the context of serous cystadenoma. The diagnosis is confirmed by histological examination. Some authors suggest labelling this phenomenon as collision tumours.

Keywords: collision tumour; fibrothecoma; ovarian cancer; serous cystadenoma; ultrasound.

Grants and funding

Italian Ministry of Health, Ricerca Corrente 202 deliberation n.219/2022.