Adsorptive Capacity, Inhibitory Activity and Processing Techniques for a Copper-MOF Based on the 3,4-Dihydroxybenzoate Ligand

Molecules. 2022 Nov 21;27(22):8073. doi: 10.3390/molecules27228073.

Abstract

Due to the fast, emerging development of antibiotic-resistant bacteria, the need for novel, efficient routes to battle these pathogens is crucial; in this scenario, metal-organic frameworks (MOFs) are promising materials for combating them effectively. Herein, a novel Cu-MOF-namely 1-that displays the formula [Cu3L2(DMF)2]n (DMF = N,N-dimethylformamide) is described, synthesized by the combination of copper(II) and 3,4-dihydroxybenzoic acid (H3L)-both having well-known antibacterial properties. The resulting three-dimensional structure motivated us to study the antibacterial activity, adsorptive capacity and processability of the MOF in the form of pellets and membranes as a proof-of-concept to evaluate its future application in devices.

Keywords: adsorption capacity; antibacterial activity; material processing; metal-organic frameworks.

MeSH terms

  • Adsorption
  • Anti-Bacterial Agents* / pharmacology
  • Copper* / chemistry
  • Ligands

Substances

  • Copper
  • 3,4-dihydroxybenzoate
  • Ligands
  • Anti-Bacterial Agents