Limited impact of a nudge comment in promoting de-escalation to first-generation cephalosporins in urinary tract infections

Antimicrob Steward Healthc Epidemiol. 2022 Sep 26;2(1):e160. doi: 10.1017/ash.2022.297. eCollection 2022.

Abstract

In this study, we evaluated the impact of a microbiology nudge on de-escalation to first-generation cephalosporins in hospitalized patients with urinary tract infections secondary to Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates with minimum inhibitory concentrations (MICs) ≤ 16 µg/mL. De-escalation to first generation-cephalosporins was uncommon at MICs = 4-16 µg/mL.