Executive summary: Japanese guidelines for allergic rhinitis 2020

Mitsuhiro Okano; Shigeharu Fujieda; Minoru Gotoh; Yuichi Kurono; Atsushi Matsubara; Nobuo Ohta; Atsushi Kamijo; Takechiyo Yamada; Yuji Nakamaru; Mikiya Asako; Daiju Sakurai; Tetsuya Terada; Shuji Yonekura; Masafumi Sakashita; Kimihiro Okubo

doi:10.1016/j.alit.2022.11.003

Executive summary: Japanese guidelines for allergic rhinitis 2020

Allergol Int. 2023 Jan;72(1):41-53. doi: 10.1016/j.alit.2022.11.003. Epub 2022 Dec 9.

Authors

Affiliations

¹ Department of Otorhinolaryngology, International University of Health and Welfare School of Medicine, Narita, Japan. Electronic address: mokano@iuhw.ac.jp.
² Division of Otorhinolaryngology Head and Neck Surgery, Department of Sensory and Locomotor Medicine, University of Fukui, Fukui, Japan.
³ Department of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan.
⁴ Department of Otolaryngology, Head and Neck Surgery, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
⁵ Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
⁶ Department of Otorhinolaryngology, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
⁷ Kamijo Allergy & ENT Clinic, Nagano, Japan.
⁸ Department of Otorhinolaryngology, Head and Neck Surgery, Akita University, Graduate School of Medicine, Akita, Japan.
⁹ Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
¹⁰ Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Osaka, Japan.
¹¹ Department of Otorhinolaryngology, Head and Neck Surgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
¹² Department of Otorhinolaryngology-Head and Neck Surgery, Osaka Medical and Pharmaceutical University, Osaka, Japan.
¹³ Department of Otolaryngology Head and Neck Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

PMID: 36509676
DOI: 10.1016/j.alit.2022.11.003

Abstract

The Practical Guideline for the Management of Allergic Rhinitis, the fist guideline for allergic rhinitis in Japan, was prepared after a symposium held by the Japanese Society of Allergology in 1993. The current 9th edition was published in 2020 and is widely used today. The most recent collection of evidence from the literature was supplemented to the revised guideline to incorporate evidence-based medicine. The revised guideline includes updated epidemiology of allergic rhinitis in Japan, a figure representing the mechanisms of allergic rhinitis in both the onset and sensitization phases with the introduction of regulatory T cells and type 2 innate lymphoid cells, practical assessment for diagnosis, new pharmacotherapy agents such as anti-IgE mAb and a new drug delivery system for antihistamines, sublingual immunotherapy for children, dual sublingual immunotherapy for house dust mites and Japanese cedar pollen extract, new classification for surgery for allergic rhinitis, and treatment and prescriptions for older adults. An evidence-based step-by-step strategy for treatment is also described.

Keywords: Allergen immunotherapy; Mechanism; Pharmacotherapy; Pollinosis; Surgery.

Publication types

Review

MeSH terms

Aged
Allergens
Animals
Child
Humans
Immunity, Innate*
Lymphocytes
Pyroglyphidae
Rhinitis, Allergic* / diagnosis
Rhinitis, Allergic* / epidemiology
Rhinitis, Allergic* / therapy

Substances

Allergens